Southcentral Division 2021
Signalment:10-year-old spayed female West Highland Terrier
History:The dog was referred for suspected nodal B-cell lymphoma based on equivocal lymph node biopsy results and generalized lymphadenopathy. Lymph node cytology was inconclusive, but the diagnosis of lymphoma was supported by flow cytometric small B-cell lymphocytosis and evidence of clonal rearrangement of the B-cell receptor via PCR. Flow cytometry, cytology, and biopsy were all suggestive of an indolent phenotype, and the patient appeared otherwise healthy with no clinical signs, so continued monitoring was elected over treatment.
Gross Lesions:A 6x7x4 cm, multilobular, well-demarcated, dark red to pale tan, firm mass effaced the cranial mediastinum and sternal lymph nodes and was firmly attached to the thoracic wall. Diffusely, there was moderate to marked enlargement of the mandibular, retropharyngeal, superficial cervical, sternal, gastric, and pancreatic lymph nodes. These lymph nodes were pale tan to dark red, semi-firm, and bulged on cut section. The spleen was diffusely enlarged with a meaty texture and was mottled pale tan to red.