Example Synoptic Report – anal sac adenocarcinoma

This report generator has not been peer reviewed - if used for diagnostic purposes, pathologists should review the information and use at their own risk.

Signalment

Relevant Clinical History

Samples Submitted

Other lymph node

Sample Measurements (cm)

Tumor Measurements (cm)

Gross Description

Sample inked?

Yes, by submitter
Yes, by laboratory
No (representative sections)

Histologic subtype

Solid subtype
Other subtype with < 50% solid component
Other subtype lacking solid component

Neoplasia at Margin?

Present
Absent

Histologic Tumor Free Distance - deep (mm)

Histologic Tumor Free Distance - peripheral (mm)

Tissue Barriers

Capsule
Other

Other Tissue Barrier(s)

Peripheral Infiltration

None
1 focus of infiltration
2 or more foci of infiltration

Peripheral infiltration is defined as neoplastic aggregates found separated from the main nodule within the peripheral connective tissue and/or muscle. From: Pradel et al. 2018

Tissues Infiltrated

Peripheral connective tissue
Perirectal musculature
Other

Other Tissue(s) Infiltrated

Lymphovascular Invasion

Not identified
Equivocal
Present

Lymphovascular Invasion Criteria Detected

Thrombus adherent to intravascular tumor
Tumor cells invading through a vessel wall and endothelium
Neoplastic cells within a space lined by lymphatic or blood vascular endothelium
Neoplastic cells in a structure confirmed to be a lymphatic or blood vessel by the use of IHC markers

Necrosis

None
Present

Estimated % Necrosis

Mitotic Count per 2.37mm2

Pleomorphism

Low - Less than 25% of cells with anisocytosis and/or anisokaryosis
Moderate - 25 - 75% of cells with anisocytosis and/or anisokaryosis
Marked - Greater than 75% of cells with anisocyosis or anisokaryosis

Per Skorupski et al. 2018

Nuclear Pleomorphism

Low - Less than 5% of cells with nuclei 2x larger than adjacent cells
Moderate - 5-10% of cells with 2x larger nuclei
Marked - More than 10% of cells with 2x larger nuclei

Per Pradel et al. 2018

Lymph Node Metastasis

No
Yes

Lymph Nodes Submitted

Lymph Nodes With Metastasis

Organ Metastasis

Not evaluated
Not detected
Present

Organs With Metastasis

E-cadherin Expression

Less than 75%
75% or more

See Polton et al. 2007 and Skorupski et al. 2018

Microscopic Description

Morphologic Diagnosis

Comments

Example Synoptic Report – anal sac adenocarcinoma

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