Noah’s Arkive – 50 most recent images – The Davis-Thompson Foundation

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IMAGE_ID	IMAGE_FRAME	Image	Contributor	Institution	Species	System	Organ	General Pathology Category	SUBSET_ID	Diagnosis	Cause	IMAGE_ACTIVE	IMAGE_VISIBILITY	IMAGE_KEYWORD	Comments	Upload Date
123,706	64,811	F64811	SAWANG KESDANGSAKONWUT	CHULALONGKORN UNIVERSITY	FELINE	CARDIOVASCULAR	HEART	HYPERTROPHY	32	Heart: hypertrophic cardiomyopathy	Unknown	1	1	Feline, hypertrophic cardiomyopathy, HCM		09/01/2023
123,707	64,812	F64812	SAWANG KESDANGSAKONWUT	CHULALONGKORN UNIVERSITY	FELINE	CARDIOVASCULAR	HEART	HYPERTROPHY/FIBROSIS	32	Heart: hypertrophic cardiomyopathy with fibroelastosis and thrombus of the left atrium	Unknown	1	1	Feline, hypertrophic cardiomyopathy, fibroelastosis, thrombus		09/01/2023
123,704	64,809	F64809	BHAVESH TRANGADIA	Kamdhenu University, Gujarat, India	BOVINE	INTEGUMENT	SKIN	INFLAMMATION	32	Lumpy skin disease (LSD) in a Gir heifer.	Capripox virus	1	1	Lumpy skin disease, LSD		08/14/2023
123,705	64,810	F64810	BHAVESH TRANGADIA	Kamdhenu University, Gujarat, India	BOVINE	INTEGUMENT	SKIN	INFLAMMATION	32	Lumpy skin disease (LSD) in a Gir heifer.	Capripox virus	1	1	Lumpy skin disease, LSD, Gir		08/14/2023
123,703	64,808	F64808	SAWANG KESDANGSAKONWUT	CHULALONGKORN UNIVERSITY	CANINE	GASTROINTESTINAL	STOMACH	NEOPLASIA, NEOPLASM, TUMOR	32	Stomach: gastric lymphoma	Unknown	1	1	Stomach, lymphoma, dog		08/09/2023
123,700	64,805	F64805	Lauren Stranahan	Texas A&M University	CANINE	GASTROINTESTINAL	STOMACH	NEOPLASIA, NEOPLASM, TUMOR	32	Gastric adenocarcinoma, signet ring variant		1	1		The signet ring variant (>50% of the tumor comprises neoplastic cells containing mucin which peripheralizes the nucleus) is one of the most common subtypes of gastric adenocarcinoma in dogs.	08/02/2023
123,701	64,806	F64806	BHAVESH TRANGADIA	Kamdhenu University, Gujarat, India	BOVINE	SKELETAL	HEAD	CONGENITAL	32	Bilateral cleft lips and palate in a female Gir calf		1	1	Bilateral cleft lips and palate, Calf, Gir	Courtesy to Dr. Rupesh Raval, Assistant Professor, Veterinary Clinical Complex, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Junagadh, Gujarat, INDIA	08/02/2023
123,702	64,807	F64807	BHAVESH TRANGADIA	Kamdhenu University, Gujarat, India	BOVINE	SKELETAL	HEAD	CONGENITAL	32	Bilateral cleft lips and palate in a female Gir calf		1	1	Bilateral cleft lips and palate, Calf, Gir		08/02/2023
123,695	64,800	F64800	EMILY BRINKER	Tufts University	BOA CONSTRICTOR	HEPATOBILIARY SYSTEM	LIVER	PARASITE	32	Hepatic hepatozoonosis	Hepatozoon sp	1	1		This amicomplexan parasite of the family Hemogregarinidae are found in a variety of snakes. In their tissue stage, where that ungergo merogony, they infect the liver and spleen. Intraeythrocytic gamonts can be found on blood smears.	07/11/2023
123,696	64,801	F64801	EMILY BRINKER	Tufts University	BOA CONSTRICTOR	HEPATOBILIARY SYSTEM	LIVER	PARASITE	32	Hepatic Hepatozoonosis	Hepatozoon sp	1	1		Hepatozoon sp. schizonts stain for PAS.	07/11/2023
123,694	64,799	F64799	BHAVESH TRANGADIA	Kamdhenu University, Gujarat, India	BOVINE	BODY AS A WHOLE	BODY AS A WHOLE	CONGENITAL	32	Brachignathism with palatoschisis		1	1	Brachignathism, Palatoschisis	Brachignathism with palatoschisis in a Jaffarabadi buffalo calf. Courtesy to Dr. Rupesh Raval, VCC, CoVSAH, Junagadh, Gujarat, INDIA	06/16/2023
123,697	64,802	F64802	BHAVESH TRANGADIA	Kamdhenu University, Gujarat, India	AVIAN	HEPATOBILIARY SYSTEM	BILE DUCT	PARASITE	32	Biliary trematodiasis		1	1	Bile duct, trematodes, lapwing	Biliary trematodiasis in a lapwing bird.	06/16/2023
123,698	64,803	F64803	BHAVESH TRANGADIA	Kamdhenu University, Gujarat, India	AVIAN	HEPATOBILIARY SYSTEM	BILE DUCT	PARASITE	32	Biliary trematodiasis		1	1	Bile duct, trematodes, lapwing	Biliary trematodiasis in a lapwing bird.	06/16/2023
123,699	64,804	F64804	BHAVESH TRANGADIA	Kamdhenu University, Gujarat, India	FELINE	RESPIRATORY	LUNG	PARASITE	32	Parasitic bronchitis		1	1	Parasite, bronchus, leopard	Parasitic bronchitis in a leopard	06/16/2023
123,692	64,797	F64797	SAWANG KESDANGSAKONWUT	Chulalongkorn University	CANINE	HEPATOBILIARY SYSTEM	GALL BLADDER	PROLIFERATIVE	32	Liver and gall bladder: cirrhosis and large gallbladder mucocele	Unknown	1	1	Liver, gall bladder, mucocele, cirrhosis		06/05/2023
123,693	64,798	F64798	SAWANG KESDANGSAKONWUT	Chulalongkorn University	CANINE	URINARY	KIDNEY	CYSTIC	32	Left kidney: renal calculus, multiple renal cysts, multifocal fibrotic interstitial nephritis (contracted kidney)	Unknown	1	1	renal calculus, renal cyst, contracted kidney, canine, kidney		06/05/2023
123,655	64,760	F64760	BRUNETTI BARBARA	University of Bologna, Italy	CANINE	NERVOUS	BRAIN	INCLUSION BODY	32	Pseudorabies (Aujeszky’s disease)	Suid Herpes Virus 1	1	1		hunting dog (Italian Segugio) which showed clinical neurological signs after eating part of a wild boar shot while hunting	05/23/2023
123,665	64,770	F64770	Schreeg	The Ohio State University	CANINE	RESPIRATORY	LUNG	NEOPLASIA, NEOPLASM, TUMOR	32	Lungs: Multifocal metastatic hemangiosarcoma		1	1	Hemangiosarcoma; metastatic neoplasia	• 13-year-old, male castrated, mixed breed dog with coughing, weakness, and decreased appetite. Euthanized. • The pulmonary parenchyma is diffusely mottled red and dark red. Throughout the parenchyma of all lung lobes are abundant multifocal to coalescing, dark red to purple, slightly raised, soft nodules ranging from pinpoint to 1x1x1 cm. • The dark red, soft appearance of the nodules and presence of similar nodules in other organs (not pictured) raises suspicion of HSA, but this cannot be definitively diagnosed without histopathology (confirmed in this case) Photo by Janice Park.	05/23/2023
123,666	64,771	F64771	Schreeg	The Ohio State University	CANINE	HEPATOBILIARY SYSTEM	LIVER	NEOPLASIA, NEOPLASM, TUMOR	32	Liver: Focal hepatocellular carcinoma; multifocal hepatocellular nodules (metastatic hepatocellular carcinoma vs. nodular hyperplasia vs. adenomas)		1	1	Hepatocellular carcinoma; hepatocellular adenoma; hepatocellular nodular hyperplasia	• 13-year-old, male castrated, mixed breed dog with coughing, weakness, decreased appetite. Euthanized. • The liver is diffusely light brown and has rounded margins. Multifocally throughout the hepatic parenchyma and occasionally extending to the capsular surface are numerous poorly demarcated, tan, soft to firm nodules ranging from pinpoint to 3.0×1.5×2.5 cm in size. The nodules in this liver demonstrate classic examples of hepatocellular nodules for which hepatocellular carcinoma, adenoma, or nodular hyperplasia should all be considered for differentials. In this case the largest nodule was histologically consistent with a hepatocellular carcinoma. This dog also had concurrent hemangiosarcoma and thyroid carcinoma in other tissues of the body (not pictured). Photo by Janice Park	05/23/2023
123,667	64,772	F64772	Schreeg	The Ohio State University	FELINE	NERVOUS	BRAIN	NEOPLASIA, NEOPLASM, TUMOR	32	Brain, Brainstem: Oligodendroglioma		1	1	Oligodendroglioma	• 5-year-old, female spayed Domestic Shorthair cat with 2-week history of disorientation, circling, and neurological deficits. Neurological exam pointed to right forebrain lesion. Euthanized. • Extending from the right telencephalon through the rostral right brainstem is a soft to gelatinous, pink to gray mass causing mass effect and deviation medially, across midline. The soft and gelatinous appearance of the mass is suggestive and supportive of an oligodendroglioma (confirmed upon histopathology). Photo by Janice Park.	05/23/2023
123,668	64,773	F64773	Schreeg	The Ohio State University	CANINE	CARDIOVASCULAR	HEART	NEOPLASIA, NEOPLASM, TUMOR	32	Heart: Focal hemangiosarcoma Lung: Metastatic hemangiosarcoma		1	1	Hemangiosarcoma; metastatic neoplasia	• 11-year-old, male castrated, mixed breed dog with behavioral changes (aggression, decreased responsivity) and tachypnea. Radiographs revealed multifocal pulmonary nodules and mid-abdominal mass. Euthanized. • Distending the right auricle is a dark red, moderately firm mass. Throughout all lung lobes are abundant, multifocal to coalescing, dark red, well-demarcated, moderately firm nodules ranging from pinpoint to 1.5×1.5×1.5 cm. Photo by Janice Park.	05/23/2023
123,669	64,774	F64774	Schreeg	The Ohio State University	CANINE	HEPATOBILIARY SYSTEM	LIVER	NEOPLASIA, NEOPLASM, TUMOR	32	Omentum, Liver, Kidney: Metastatic hemangiosarcoma		1	1	Hemangiosarcoma; metastatic neoplasia	• 11-year-old, male castrated, mixed breed dog with behavioral changes (aggression, decreased responsivity) and tachypnea. Radiographs revealed multifocal pulmonary nodules and mid-abdominal mass. Euthanized. • Multifocally throughout the hepatic parenchyma and within the renal cortices and superficial medullae bilaterally are numerous multifocal to coalescing, dark red, well-demarcated, moderately firm, slightly raised, variably sized nodules. Within the omentum is a 4x4x4 cm, moderately firm to soft, dark red mass. Photo by Janice Park.	05/23/2023
123,670	64,775	F64775	Schreeg	The Ohio State University	CANINE	HEMATOPOIETIC	SPLEEN	HYPERPLASIA	32	Spleen: Focally extensive vascular hamartoma		1	1	Hamartoma; splenic nodule	• 8-year-old, intact male, mixed breed dog with acute lethargy, respiratory distress, pallor, and clinically diagnosed with hypovolemic shock. Euthanized. • Arising from and locally expanding the splenic parenchyma is a single large, soft, raised, dark red mass measuring 10.5×11.4×3.8 cm. Differentials for this splenic mass could include hemangiosarcoma, hematoma, nodular hyperplasia, or less likely benign vascular proliferations (e.g. hemangioma, vascular hamartoma). In our experience the latter diagnoses are uncommon. In this case, the histology was most supportive of a vascular hamartoma. Regardless of the benign nature of the mass, in this case there was rupture of the mass resulting in hemoabdomen, demonstrating that even benign splenic nodules can result in morbidity and mortality. Photo by Janice Park.	05/23/2023
123,671	64,776	F64776	Schreeg	The Ohio State University	CANINE	HEMATOPOIETIC	SPLEEN	NEOPLASIA, NEOPLASM, TUMOR	32	Spleen: Diffuse splenomegaly with multifocal splenic nodules (histologically confirmed as lymphoma); multifocal to coalescing siderotic plaques		1	1	Lymphoma; splenic lymphoma; siderotic plaques; Gandy-Gamma nodules	• 10-year-old, female spayed Greyhound with history of osteoblastic osteosarcoma. CT revealed splenomegaly with multifocal nodules, peritoneal effusion, gas bubbles, and segmental jejunal changes. Euthanized. • The spleen is subjectively enlarged and irregular. Multifocally throughout the spleen are numerous firm, variably sized, dark pink to tan, slightly raised nodules arising from the splenic parenchyma and raising the capsular surface. Throughout the capsular surface of the spleen are abundant multifocal to coalescing, tan, flat, smooth, pinpoint to 3×3 mm foci (siderotic plaques). • Final diagnosis was T-cell lymphoma (CD3+, CD20-) in the spleen (as well as small intestines). This image shows malignant neoplasia manifesting as a combination of diffuse splenomegaly and ill-defined nodules that is suggestive of a round cell neoplasm, and in this case was confirmed to represent lymphoma. In addition, numerous siderotic plaques, a benign lesion, are highlighted in this image. Photo by Janice Park.	05/23/2023
123,672	64,777	F64777	Schreeg	The Ohio State University	EQUINE	URINARY	OMENTUM	NEOPLASIA, NEOPLASM, TUMOR	32	Omentum, Diaphragm, Spleen, Liver, Lumbosacral Vertebrae: Metastatic squamous cell carcinoma/carcinomatosis		1	1	Squamous cell carcinoma; metastatic neoplasia; metastatic carcinoma; carcinomatosis	• 15-year-old draft horse cross mare with history of reported urothelial carcinoma of the urinary bladder. Euthanized. • Multifocally throughout the diaphragm, omentum, and superficial parenchyma and capsular surfaces of the liver and spleen are numerous multifocal, umbilicated, multilobulated, pale tan to white, firm to friable masses ranging from 5x5x5 mm to approximately 7x6x6 cm. Upon sagittal sections, the medullary cavities of the lumbosacral vertebrae are subjectively mottled red and tan, with 75% of the medullary cavity being tan. Not pictured: In this case, the peritoneal cavity contained approximately 5 L of red to orange-tinged, semi-opaque watery, fluid (peritoneal effusion). The urinary bladder wall was diffusely moderately thickened, and is focally expanded by a 12x9x7 cm, multilobulated, transmural, pale tan to white, firm to friable, mass. The mucosal aspect of the mass was coated in a moderate amount of tan to pink, opaque, turbid material. The horse had been presumptively diagnosed antemortem with urothelial carcinoma; however, histologic evaluation of the neoplasms was consistent with squamous cell carcinoma. IHC of urinary bladder mass was negative for uroplakin III. Determined likely squamous cell carcinoma based on presence of squamous differentiation of neoplastic cells and the IHC results. Metastatic neoplasia was confirmed on histology for all tissues except the lumbar spine (sections of which were histologically unremarkable), although this was still suspected based on gross appearance. In ruminants, urinary bladder neoplasms can be associated with bracken fern ingestion. Photo by Janice Park.	05/23/2023
123,673	64,778	F64778	Schreeg	The Ohio State University	CANINE	GASTROINTESTINAL	MESENTERY	NEOPLASIA, NEOPLASM, TUMOR	32	Mesentery (Jejunum, Ileum): Focally extensive neoplasia (histologically confirmed as a mast cell tumor); Moderate, acute, segmental melena		1	1	Visceral mast cell tumor; melena	• 10-year-old, female spayed, mixed breed dog with neoplastic peritoneal effusion. Euthanized. • Within the mesentery of the jejunum and ileum is an 8x6x4cm, poorly-demarcated, infiltrative, soft, mottled dark red and tan, multilobulated mass that has a 1×1 cm, friable rupture site. The distal ileum and cecum contains a moderate amount of dark red to black, viscous fluid (melena). Grossly a variety of neoplastic differentials were considered. Histologically, the neoplasm was consistent with a round cell tumor, and neoplastic cells had strong and diffuse membranous to cytoplasmic labeling for cKIT, and were uniformly negative for CD3, CD20, and MUM1, consistent with diagnosis of a visceral mast cell tumor. Photo by Janice Park.	05/23/2023
123,674	64,779	F64779	Schreeg	The Ohio State University	CANINE	GASTROINTESTINAL	STOMACH	DISPLACEMENT	32	Stomach and spleen: Gastric dilatation and volvulus with regionally extensive ischemic necrosis and splenic displacement		1	1	Gastric dilation and volvulus; GDV	Signalment and history: 14-year-old neutered male mixed breed dog with a 2 day history of vomiting and retching, lethargy, and anorexia. Description: Upon opening in right lateral recumbency, the stomach is markedly gas distended and rotated approximately 270 degrees clockwise on the mesenteric axis with the pylorus located craniodorsally and gastric fundus located ventrally. The gastric serosa and mucosa are regionally red to dark red with the fundus more affected. The serosal surface of the duodenum is diffusely red to dark red. The spleen is displaced caudally and to the right of midline. Photo by Allysa Cole.	05/23/2023
123,675	64,780	F64780	Schreeg	The Ohio State University	CANINE	NERVOUS	BRAIN	CONGENITAL	32	Brain: Marked bilateral ventriculomegaly (hydrocephalus)		1	1	Hydrocephalus	Signalment and history: 3-month-old male pit bull terrier. Acute onset of seizures, with 6 seizures on day of presentation Description: The left and right lateral ventricles are markedly dilated, with the left and right cortex measuring 1 mm and up to 4 mm in thickness, respectively. Photo by Allysa Cole.	05/23/2023
123,676	64,781	F64781	Schreeg	The Ohio State University	BOVINE	GASTROINTESTINAL	HEAD	CONGENITAL	32	Hard and soft palate: Palatoschisis (cleft palate)		1	1	Cleft palate; palatoschisis	Signalment and history: 1-day-old mixed breed beef calf born with severe angular limb deformities. The calf was unable to stand but had a suckle reflex. The cow has had two previously healthy calves, though 4 ewes on the farm birthed lambs with spinal deformities and absent tails. Description: There is incomplete closure of the hard and soft palate with a 14 cm x 3.5 cm defect communicating with the nasal cavity. Comments: Differentials for arthrogryposis in cattle include Akabane virus, Schmallenberg virus, Cache Valley virus, Bluetongue virus, or teratogenic plants. Viral etiologies are more likely to have gross lesions within the central nervous system, which were not seen in this case, so teratogenic plants were considered the most likely cause. Photo by Allysa Cole.	05/23/2023
123,677	64,782	F64782	Schreeg	The Ohio State University	CANINE	RESPIRATORY	LUNG	THROMBUS, thrombi/EMBOLUS, emboli	32	Lung: Focal pulmonary thromboembolism		1	1	pulmonary thromboembolism; PTE	Signalment and history: 12-year-old spayed female mixed breed dog that presented for a routine cholecystectomy. During surgery, she developed intermittent tachypnea and acutely decompensated overnight with development of marked ascites. Description: Occluding a distal pulmonary artery of the right caudal lung lobe is a 20 mm x 5 mm x 5 mm, rough, tan to red, soft, coagulum that is moderately adhered to the intimal surface Photo by Allysa Cole.	05/23/2023
123,678	64,783	F64783	Schreeg	The Ohio State University	BOVINE	CARDIOVASCULAR	AORTA	NORMAL	32	Ductus arteriosus: Normal neonatal finding		1	1	Ductus arteriosus; patent ductus arteriosus	Signalment and history: 6-day-old male Maine Anjou calf Description: The ductus arteriosus contains a moderate amount of friable, red, fibrous tissue obstructing the lumen between the pulmonary artery and aorta. Comments: Functional closure of the ductus arteriosus occurs shortly after birth, and complete anatomic closure is mediated by increased oxygen tension and inhibition of prostaglandin within the first weeks of life. Photo by Allysa Cole.	05/23/2023
123,679	64,784	F64784	Schreeg	The Ohio State University	CANINE	CARDIOVASCULAR	HEART	DEGENERATION	32	Heart: Severe mitral valve endocardiosis with moderate left atrial dilation		1	1	Endocardiosis; mitral valve endocardiosis; mitral valve disease; myxomatous degeneration	Signalment and history: 14-year-old neutered male Pekingese that presented for progressive coughing, wheezing, and difficulty breathing. It was clinically found to have a 4/6 left apical systolic murmur and a collapsing trachea. Description: The mitral valve leaflets contain numerous, multifocal to coalescing, 3-6 mm in diameter, smooth, white, shiny nodules. The left atrium and left auricle are subjectively mildly enlarged. Photo by Allysa Cole.	05/23/2023
123,680	64,785	F64785	Schreeg	The Ohio State University	FELINE	URINARY	KIDNEY	DISTENTION, DILATION, dilatation	32	Kidneys: Moderate bilateral hydronephrosis and hydroureter		1	1	Hydronephrosis; hydroureter	Signalment and history: 5-month-old spayed female Siamese cat that presented weak, lethargic, and ataxic since spay procedure. Serum chemistry revealed severe hyperkalemia, hyperphosphatemia, and azotemia. Description: The left and right kidneys are subjectively moderately enlarged, with mild to moderate enlargement of the renal pelves. Bilaterally the ureters are mildly and diffusely dilated and filled with clear, transparent, watery fluid with a diameter of up to 5 mm. The ureters contain no overt obstruction between the renal pelvis and urinary bladder, and the proximal urethra is patent. Comments: The underlying cause of hydronephrosis and hydroureter was not identified on gross or histologic evaluation. The clinic was concerned for accidental surgical ligation in this case, but there was no ligation noted or evidence of inflammation expected with a transient ligation, so dysplasia is prioritized as a cause of lesions.	05/23/2023
123,681	64,786	F64786	Schreeg	The Ohio State University	FELINE	CARDIOVASCULAR	AORTA	THROMBUS, thrombi/EMBOLUS, emboli	32	Descending aorta at level of external iliac arteries: Focal acute thromboembolism		1	1	Saddle thrombus; aortic thromboembolism; ATE; hypertrophic cardiomegaly; HCM	Signalment and history: 12-year-old spayed female domestic longhair cat that presented acutely paraplegic. Description: Attached to the endothelial surface of the distal descending aorta at the level of the external iliac arteries is a dark red to tan, multilobular, rough, firm, coagulum that occludes both iliac arteries and distal descending aorta. The thrombus extends 2.1 cm cranial to the bifurcation, 0.2 cm into the left iliac artery, and 0.6 cm into the right iliac artery. Comments: Gross postmortem examination also identified marked cardiomegaly with moderate concentric left ventricular hypertrophy and left atrial dilation, which is the most likely contributing factor to the thromboembolism seen in the descending aorta. Photo by Allysa Cole.	05/23/2023
123,682	64,787	F64787	Schreeg	The Ohio State University	CANINE	SKELETAL	FEMUR	NEOPLASIA, NEOPLASM, TUMOR	32	Proximal femur: Telangiectatic Osteosarcoma		1	1	osteosarcoma; telangiectatic osteosarcoma	1-year-old MN Standard Poodle mix; Historical FHO surgery and has not been the same since. Was noted to be in respiratory distress by owner and died naturally. The head of the femur and proximal femoral neck are absent, and the surrounding soft tissues are markedly expanded by dark red fluid. The proximal end of the remaining femur is irregular and roughened, with segmental loss of the cortical bone. This region is surrounded by a thick, firm white capsule-like tissue that contains thin, linear to nodular, multifocal hard white tissue (bone). On section, the medullary space of the proximal end of the remaining femur (diaphyseal bone) contains abundant dark red to red to pale tan tissue, and, more distally, the medullary space is regionally filled with hard, white tissue (endosteal bone). There are multifocal bone spicules extending from the cortical surface, proximally. Not shown: In addition to the provided image, the thorax contained 700ml of dark red, opaque, watery fluid (hemorrhage, 26% blood volume). The lungs and mediastinum contained dozens of multifocal, pale, tan, round, firm, well demarcated nodules measuring from 0.5 x 0.5 x 0.5 cm to 1.5 x 1.5 x 1 cm and similar multifocal, dark red, round, firm, well demarcated nodules measuring from 2 x 2 x 2 cm to 4 x 5 x 3 cm. On cut section, the nodules released a dark red, moderately viscous fluid. This was consistent with metastatic osteosarcoma. This is an aggressive tumor primarily of long bones in dogs with primary metastasis to the lungs. Photo by Sophie Hopkins.	05/23/2023
123,683	64,788	F64788	Schreeg	The Ohio State University	EQUINE	SKELETAL	BONE	INFLAMMATION/PROLIFERATIVE	32	Right calcaneus: Marked, chronic, regionally extensive osteomyelitis cartilage erosion and incomplete non-displaced cortical fracture		1	1	Osteomyelitis; fracture	7-year-old Quarter horse gelding; The horse presented with a non-weight bearing right hind lameness. The limb was diffusely swollen, edematous, warm, consistent with a cellulitis. Bloodwork indicated marked inflammation and the horse was treated with intravenous antibiotics without improvement. An abscess was identified distal and caudle to the calcaneus with a calcaneal defect. A septic bursitis was diagnosed and euthanasia was elected. On the caudocranial aspect of the calcaneus there is an incomplete, nondisplaced, mildly comminuted, fracture creating a round depression and defect through the cortical bone. On sagittal sectioning, the medullary cavity of the calcaneus is mottled dark red to tan with rare foci of red discoloration radiating through the cortex. Just deep to the cortical fracture is a 0.5cm semi-circle of white firm matrix (sclerosis). Histologic evaluation confirmed a fibrinosuppurative osteomyelitis with fibroplasia. Photo by Sophie Hopkins.	05/23/2023
123,684	64,789	F64789	Schreeg	The Ohio State University	EQUINE	SKELETAL	BONE	DEGENERATION	32	Left front fetlock, first phalanx: Marked, chronic, focal articular cartilage ulceration with osteosclerosis		1	1	cartilage erosion; cartilage ulceration; osteosclerosis; degenerative joint disease; osteoarthritis	9-year-old Quarter Horse mare; History of lameness arising at a competition that did not resolve. There is a focal, irregular, well demarcated 0.7 x 0.3cm ulceration of the articular cartilage centered on the proximomedial condyle of the first phalanx. On sagittal sectioning of the first phalanx, deep to the cartilage ulceration, there is a 1cm semi-circle of white firm matrix immediately subjacent to the ulceration (sclerosis). Additional gross findings support the diagnosis of osteoarthritis: The fascia overlying the dorsomedial aspect of the first phalanx extending from the metacarpophalangeal joint to mid-diaphysis is moderately thickened. Arising from the underlying bone are multifocal to coalescing irregular, white, firm pinpoint to 0.5cm diameter nodules. Free within the metacarpophalangeal going are two firm, smooth, tan ovoid fragments of tissue measuring 1.0 x 0.4 x 0.2cm and 0.4 x 0.2 x 0.2cm (cartilaginous joint mice). The synovial tissue lining the metacarpophalangeal joint is enlarged and dark red.	05/23/2023
123,685	64,790	F64790	Schreeg	The Ohio State University	CANINE	GASTROINTESTINAL	INTESTINE-SMALL	DISPLACEMENT	32	Duodenum, jejunum: Obstructive linear foreign body with duodenal and jejunal plication		1	1	Linear foreign body	2-year-old FS Golden Retriever; History of vomiting and lethargy and natural death. There is a minimal amount of dark green, watery fluid in the peritoneal cavity. The duodenum is plicated at the base of the pylorus and plications extend into the proximal jejunum. There is a piece of green fabric measuring 52cm in length anchored within the pylorus and extending through the jejunum. Photo by Sophie Hopkins.	05/23/2023
123,686	64,791	F64791	Schreeg	The Ohio State University	FELINE	GASTROINTESTINAL	INTESTINE	NEOPLASIA, NEOPLASM, TUMOR	32	Jejunum, mesenteric lymph node: Lymphoma		1	1	Lymphoma; enteropathy; gastrointestinal; intestinal	10-year-old FS Domestic Shorthair; History of anorexia and collapse. Focally circumferentially expanding the wall of the mid-jejunum is a tan, soft, round mass measuring 3.5x4x3cm. On cut section, there is complete loss of normal bowel wall layering, and the mass is homogenously tan with a 1cm diameter lumen that is lined by a granular, rough surface and contains scant green to black ingesta. The mesenteric lymph node is markedly enlarged (3x4x3cm) and diffusely pale tan, round, and soft. On cut section, the lymph node lacks corticomedullary distinction has a 0.5cm diameter central area that is friable and yellow. Histopathology confirmed the grossly diagnosis of lymphoma for the mass in the jejunum. The top consideration for lymphoma subtype based on location and cell size is enteropathy associated T cell lymphoma (EATL) type I (intestinal large T cell lymphoma). Lymphoma within the liver and lymph nodes was also present in this case, in addition to a separate small T cell enteropathy lymphoma (EATL type II). Photo by Sophie Hopkins.	05/23/2023
123,687	64,792	F64792	Schreeg	The Ohio State University	FELINE	HEPATOBILIARY SYSTEM	GALL BLADDER	OBSTRUCTION	32	Gallbladder, liver: Severe, chronic biliary outflow obstruction with severe gallbladder ectasia and extrahepatic cholestasis Body as a whole: Marked, diffuse icterus		1	1	gallbladder obstruction; extrahepatic obstruction; cholestasis; icterus; jaundice	13-year-old MN Domestic Shorthair; Narrowing of bile duct and elevation in liver enzymes. Declined and was euthanized. The subcutaneous fat is diffusely yellow. The gallbladder is severely distended and tortuous, occupying 60% of the abdominal cavity, and is filled with dark green, mucoid material (bile). The liver with gallbladder attached weighs 763g (17.7% body weight). The liver is firm, has a moderately enhanced reticular pattern and exudes dark green mucoid material on cut section. On histologic evaluation at the base of the gallbladder, a neuroendocrine proliferation most consistent with a carcinoid was identified, and was thought to be the most likely cause of obstruction and subsequent extrahepatic biliary ectasia. Photo by Sophie Hopkins.	05/23/2023
123,688	64,793	F64793	Schreeg	The Ohio State University	EQUINE	GASTROINTESTINAL	COLON	DISPLACEMENT	32	Large colon: Left dorsal displacement (AKA nephrosplenic ligament entrapment)		1	1	left dorsal displacement; nephrosplenic ligament; colic	2-year-old Standardbred mare; Presented for colic, workup suggested large colon displacement. Concern for internal abscesses. The left portion of the large colon is dorsally displaced and entrapped over the nephrosplenic ligament. The apex of the cecum is visible. The right ventral colon and small colon are moderately gas distended and obscure visualization of the pelvic flexure. Not shown: This horse also had significant intestinal parasitism, including gastric bots, Strongylus vulgaris verminous arteritis, cecal cestodes, and encysted nematode larvae (presumed strongyles) in the cecum, right ventral colon, and body wall. It is unclear if these contributed/predisposed to left dorsal displacement in this case. It is also possible that these parasites were contributors to colic. Photo by Sophie Hopkins.	05/23/2023
123,689	64,794	F64794	Schreeg	The Ohio State University	BONOBO	CARDIOVASCULAR	AORTA	DEGENERATION/RUPTURE	32	Aorta: Marked, multifocal tunica intima tear with false lumen formation (aortic dissection); Marked regionally extensive atherosclerosis Heart: Moderate left ventricular hypertrophy		1	1	atherosclerosis; aortic dissection; aneurysm; concentric hypertrophy	40-year-old female intact Bonobo; Aortic dissection confirmed on CT. Developed pulmonary edema during anesthesia and could not be recovered. The left ventricular free wall of the heart measures 2cm in thickness and the right ventricular free wall measures 0.5cm in thickness. The proximal ascending aorta has a 5.5×5.5×4.5cm dilation. The proximal aorta just past the aortic valve has two horizontal intimal tears with ragged edges measuring 1cm and 1.2cm. At the level of the branching of the branchiocephalic artery there is a 2cm horizontal tear through the intimal and medial layers with ragged edges. The aorta 3cm distal to the brachiocephalic artery branching has a tear with rounded edges through the intimal and medial layers creating a marked outpouching associated with the previously measured dilation in the proximal ascending aorta. There is a smooth band of aortic intimal tissue just distal to the aforementioned tear measuring 0.7cm in width. The intimal surface of the descending aorta is multifocally yellow, hard, and wrinkled, most severely affecting the distal segment surrounding the bifurcation of the femoral arteries. Not shown: The thorax contains approximately 225mL of translucent red watery fluid. The pericardial sac and mediastinum and mildly thickened with edema. The pericardial sac is expanded by approximately 25mL of translucent yellow, watery fluid. Photo by Sophie Hopkins.	05/23/2023
123,690	64,795	F64795	Schreeg	The Ohio State University	ALPACA	URINARY	KIDNEY	INFLAMMATION	32	Kidney: Severe, chronic, multifocal to coalescing, pyogranulomatous nephritis		1	1	Bacterial nephritis; embolic nephritis; tubulointerstitial	Bilaterally, the capsular surface of the kidneys have enumerable tan to white-grey round, raised, soft nodules that measure from pinpoint to 3mm diameter. On cut section, the nodules are present throughout the cortex. There are numerous linear, thread-width, bright red streaks throughout the medulla. Histologically, there was a tubulointerstitial nephritis with intralesional bacteria; both embolic showering (septicemia) as well as possibly ascending infection were considered as possible routes of infection. Photo by Sophie Hopkins.	05/23/2023
123,691	64,796	F64796	Schreeg	The Ohio State University	CANINE	HEPATOBILIARY SYSTEM	GALL BLADDER	HYPERPLASIA	32	Gallbladder: Moderate diffuse cystic mucinous hyperplasia		1	1	cystic mucinous hyperplasia; cystic hyperplasia; gallbladder hyperplasia	9 year old female spayed beagle, acute vomiting with aspiration pneumonia. Cystic mucinous hyperplasia was identified in the gallbladder and was considered incidental to decline. This lesion is present as part of the syndrome of gallbladder mucocele, but also can be present separate to mucocele, as in this case. Photo by Sophie Hopkins	05/23/2023
123,648	64,753	F64753	Schreeg	The Ohio State University	CANINE	URINARY	KIDNEY	DYSPLASIA, dysplastic	32	Kidney: Bilateral marked diffuse chronic cortical atrophy with diffuse fibrosis, multifocal cortical cysts, hydronephrosis and mineralization (consistent with renal dysplasia)		1	1	Renal dysplasia	4-year-old female spayed mixed breed dog, several year history of renal dysplasia and fibrous osteodystrophy Bilaterally, the capsular surface of the kidneys are pale pink to tan, firm, and have severely lobulated subcapsular surface and multifocal opaque foci throughout the capsule (capsular fibrosis) . Both kidneys are similar in size (5cm x 2cm x 2cm). On the ventral half of the left kidney’s capsular surface, there is a tan wrinkly hard plaque-like focus (2cm x 1.5cm x0.3cm; mineralization). On cross section, both kidneys have few ( hyperparathyroidism –> bone resorption and fibrous osteodystrophy Photo by Yea Ji Jeong	05/22/2023
123,649	64,754	F64754	Schreeg	The Ohio State University	CANINE	ENDOCRINE	PITUITARY	NEOPLASIA, NEOPLASM, TUMOR	32	Ventral brain, pituitary gland, third ventricle: Focal pars intermedia adenocarcinoma with ventricular invasion and dilation		1	1	Pituitary adenocarcinoma	12-year-old male neutered mixed breed dog, 2 months history of declining heath due to splenic mass and cardiomegaly. Increased lethargy and inappetence, having accidents in the house. On the ventral surface of the brain at the region of the pituitary gland, there is a focal mottled dark red to tan to pink soft and friable well demarcated mass (2 x 2.5 x 1cm). The mass extends into the third ventricle and easily detaches from the ventricle upon mild manipulation; the portion of the mass within the third ventricle is regionally dark red with 10-20 pinpoint yellow foci scattered throughout. The third ventricle is moderately distended as viewed from the ventral surface of the brain when the mass is detached. A portion of the pituitary gland that remains in the calvarium measures 0.8 x 0.8 x 0.3mm and has a similar appearance as described in the mass above.	05/22/2023
123,650	64,755	F64755	Schreeg	The Ohio State University	CANINE	CARDIOVASCULAR	HEART	DYSPLASIA, dysplastic	32	Heart: Diffuse severe chronic sub-aortic stenosis with severe segmental post-stenotic aortic dilatation and left ventricular concentric hypertrophy		1	1	Aortic stenosis; left ventricular concentric hypertrophy	1-year-old male Boerboel dog, history of aortic stenosis, died suddenly at home. The heart weighs 664g (0.98% of the body weight). The lumen of the left ventricular outflow tract is severely reduced and aortic valve leaflets are diffusely thickened (2x), opaque, and moderately firm. Extending from the ventral aspect of the aortic valve leaflets ventrally is a thick, firm, well-demarcated, fibrillar, circumferential, 4 cm long, raised, plaque-like band of pale tan fibrous connective tissue firmly adhered to the endocardium. The proximal aorta is segmentally dilated and the wall is segmentally thinner in this region. The proximal left coronary artery branching from the aorta is markedly dilated and measures 1cm in diameter (right coronary artery diameter measures 4mm). The left ventricular free wall is diffusely thickened (widest dimension: 3cm). Photo by Yea Ji Jeong	05/22/2023
123,651	64,756	F64756	Schreeg	The Ohio State University	CANINE	SKELETAL	BONE-MAXILLA	NEOPLASIA, NEOPLASM, TUMOR	32	Facial mass: Osteosarcoma with focally extensive maxillary osteolysis and dorsal displacement of the left orbital globe.		1	1	Osteosarcoma	1-year-old spayed female Doodle mix. On the left side of the face, there is a 9 x 11cm hard spherical raised mass which partially extends into the oral cavity near the left caudal maxilla. The mass extends dorsally to the left lower orbital rim and the left eye is severely displaced dorsally. On a dorsal cross section, the mass is surrounded by approximately 0.3-0.5cm pale hard bony capsule and contains a white hard radiating foci with a pale yellow bony core and associated osteolysis. The medial half of the mass interfaces a green to pale black moderately soft gelatinous to friable material (2.5 x 2cm) and extends caudally into the left ear canal. The mass compresses the nasal cavity and the nasal septum and the turbinates are mildly to moderately shifted to the right progressively toward the caudal portion. Photo by Yea Ji Jeong.	05/22/2023
123,652	64,757	F64757	Schreeg	The Ohio State University	FELINE	NERVOUS	BRAIN	NEOPLASIA, NEOPLASM, TUMOR	32	Brain: Focally extensive cerebrocortical lymphoma with surrounding edema		1	1	Lymphoma	15-year-old Male neutered Domestic shorthair cat, left pyriform mass with edema The right ventrolateral aspect of the brain, especially the white matter, is expanded by a focally extensive white ill-defined mass. The brain parenchymal adjacent to the mass is replaced by clear gelatinous material (edema). Photo by Yea Ji Jeong.	05/22/2023
123,653	64,758	F64758	Schreeg	The Ohio State University	CANINE	SKELETAL	BONE-MAXILLA	NEOPLASIA, NEOPLASM, TUMOR	32	Maxilla: Focal multilobular tumor of the bone with mandibular displacement		1	1	Multilobular tumor of bone; multilobular osteochondrosarcoma	12-year-old female Poodle, 5 x 5.5 mass over the right caudal maxilla/mandible Arising from the right caudal maxilla overlying the right zygomatic arch and the mid to caudal mandible is a focally extensive firm round mass (5.5 x 5 x 2 cm). The mass has a mildly bumpy and irregular surface, and wraps ventrally and medially around the mandible, resulting in moderate medial displacement of the caudal mandible. The cranial margin of the mass has a focal soft to mildly firm pale somewhat translucent tissue which extends cranioventrally into the oral cavity and compresses the right distal upper and lower molars (110 and 411). On cross sections, the mass is bi-lobulated and diffusely pale tan to white with an internal granular (‘rice grain’) appearance. At the level of the right upper premolar 108 and lower molar 409, the core of the mass extending from the level of the root of 108 to the lateral surface of the mandible is diffusely gray to dark gray with increased translucency (necrosis); in this region, the overlying gingival mucosa is bright red and wet (ulceration). There is severe dental plaque accumulation affecting all teeth. Photo by Yea Ji Jeong.	05/22/2023
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